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Physicochemical Approaches to the Characterization of Pharmaceutical Systems New Book

  • Pharmaceutical Preformulation and Formulation

    Pharmaceutical Preformulation and Formulation
    Mark Gibson

    The results of characterization studies carried out will influence their product design. However, in the interest … While there are many traditional approaches to dosage form design, newer approaches based on expert systems that require knowledge of the physicochemical properties are being employed to speed up development (Rowe, 1998; Pe ́rez et al., 2006; Branchu et al., 2007). Expert systems are …

  • HPLC for Pharmaceutical Scientists

    HPLC for Pharmaceutical Scientists
    Yuri V. Kazakevich, Rosario LoBrutto

    There are two main approaches to the prediction of retention times based on chemical structures. Both use a training set of compounds to characterize the system prior to creation of a prediction expression. The first (used in ChromSword ®) …

  • Pharmaceutical Suspensions

    Pharmaceutical Suspensions
    Alok K. Kulshreshtha, Onkar N. Singh, G. Michael Wall

    The focus of this chapter is on the tools, technologies, and approaches utilized in transition of compounds from drug discovery through preclinical … Metabolism,. Excretions. and. Toxicity. Profiling. 5.2.1. Physicochemical. Characterization. of. New. Chemical. Entities. in … Only in very exceptional cases, there are time and resources available to develop special drug delivery systems to optimize exposure.

  • Developing Solid Oral Dosage Forms

    Developing Solid Oral Dosage Forms
    Yihong Qiu, Yisheng Chen, Geoff G.Z. Zhang, Lirong Liu, William Porter

    This book is intended for pharmaceutical professionals engaged in research and development of oral dosage forms.

  • Pharmaceutical Manufacturing Handbook

    Pharmaceutical Manufacturing Handbook
    Shayne Cox Gad

    Full characterization of such systems is a tedious task requiring a large number of experiments [34]. One acceptable approach for representing such systems is by fixing the mass ratio of two components (such as the two amphiphiles) and as such considered a single component. … RELATED SYSTEMS The physicochemical and analytical techniques used to characterize MEs and related systems could …

  • Pharmaceutical Dosage Forms - Tablets, Third Edition

    Pharmaceutical Dosage Forms – Tablets, Third Edition
    Larry L. Augsburger, Stephen W. Hoag

    Giron D. Thermal analysis and calorimetric methods in the characterization of polymorphs and solvates. Thermochim Acta … Physicochemical characterization of nedocromil bivalent metal salt hydrates.1. … Hancock BC, Zografi G. Characteristics and significance of the amorphous state in pharmaceutical systems. J Pharm …

  • Novel Approaches for Drug Delivery

    Novel Approaches for Drug Delivery
    Keservani, Raj K., Sharma, Anil K., Kesharwani, Rajesh Kumar

    Studies on a high encapsulation of colchicine by a niosome system. … Safety Aspects of Non‐ionic Surfactant Vesicles: A Toxicity Study Related to the Physicochemical Characteristics of … The Journal of Pharmacy and Pharmacology, …

  • Pharmaceutical Nanotechnology

    Pharmaceutical Nanotechnology
    Costas Demetzos

    In a recent study, Rowland and coworkers [31] mention: “A drug delivery system is the pharmacotechnological system that carries bioactive … According to our approach, the development process of delivery nanosystem development should be based on the following three … Even though the nanosystem physicochemical characteristics are sufficiently evaluated by the material science and science of …

  • Transport Processes in Pharmaceutical Systems

    Transport Processes in Pharmaceutical Systems
    Gordon L. Amidon, Ping I. Lee, Elizabeth M. Topp

    Several drugs covering a wide range of absorption characteristics, from poorly absorbed compounds to those with virtually complete absorption, … to forecast the absorption trends and to identify the critical limiting physicochemical properties, particularly for poorly soluble drugs. … STEADY-STATE MODEL A. Macroscopic Mass Balance Approach Although the pH-partition hypothesis and the absorption …

  • Amorphous Solid Dispersions

    Amorphous Solid Dispersions
    Navnit Shah, Harpreet Sandhu, Duk Soon Choi, Hitesh Chokshi, A. Waseem Malick

    Int J Pharm 357:77–84 Urbanova M, Brus J, Sedenkova I, Policianova O, Kobera L (2013) Characterization of solid polymer dispersions of … Taylor LS (2011) Application of mid-IR spectroscopy for the characterization of pharmaceutical systems. … Strzemiecka B, Adamska K, Milczewska K (2009) Inverse gas chromatography as a source of physiochemical data. … New approaches to the characterization of drug candidates by solid-state NMR, Pharmaceutical Sciences Encyclopedia.

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